This indicates that GAP-43-related synaptic changes do not lead to a widespread tau accumulation but specifically facilitate its spread along neural pathways. This finding is particularly significant ...

A long-standing goal of neuroscience is to understand how molecules and cellular structures on a microscale give rise to communication between brain regions at the macroscale.

CAMBRIDGE, Mass.--(BUSINESS WIRE)--Rodin Therapeutics today announced the launch of a clinical trial to assess the performance of a new PET ligand that can measure synaptic density in the living ...

The same kind of neurons can have completely different wiring diagrams in the rat and mouse, as mice lack intercellular molecular channels known as gap junctions, researchers at Karolinska Institutet ...