The central dogma of molecular biology is linear, moving from DNA to mRNA to protein. It's straightforward on an individual-gene level: turn on a gene, make mRNA, create proteins from the mRNA.

The central dogma processes of DNA replication, transcription, and translation are responsible for the maintenance and expression of every gene in an organism. An orthogonal central dogma may ...

The central dogma of biology, in its simplest form, is that genomic information is transcribed to RNA, ... Chemical biology has been essential to discoveries in the area of gene expression.

Gene expression can be regulated by various cellular processes with the aim to control the amount and nature of the expressed genes. ... Gene expression, central dogma of molecular biology ...

The central dogma of gene expression states that information flows in a single direction, from the inherited genetic code (DNA) to functional proteins via ribonucleic acid (RNA) intermediaries. 4, 5 ...

The previous paradigm was given in what is called the central dogma. DNA—> RNA—> Protein—> Phenotype The dogma was enshrined in Jim Watson’s 1965 epic textbook The Molecular Biology of the ...

Central dogma: The clinical view ... makes it clear that any form of current classical one-by-one gene status assessment will not be adequately informative ... accommodating the actual vast ...

In 1958, five years after he helped discover the double helix structure of DNA, Francis Crick coined the term "Central Dogma" to characterize the all-important cellular processes whereby DNA is ...

But its location and effect on gene expression reflect a new form of epitranscriptome control and suggest an even larger cellular “control panel.” “The discovery of m1A is extremely important, not ...

Patients with treatment-resistant central centrifugal cicatricial alopecia saw improvement in symptoms and gene expression, suggesting the potential of metformin as a new treatment option.