A key function of IRS proteins in peripheral tissues is to couple insulin receptor activation to signaling via the PI3K signal transduction pathway, and in neurons, PI3K is implicated as a key ...

A fascinating study has discovered an insulin-suppressing protein that can help extend the lifespan of some ants by 500%. It revealed that in a certain species of ant this anti-aging pathway is ...

Insulin orchestrates blood glucose levels by signaling fat and muscle cells to absorb the sugar and liver cells to stop pumping it out, so most research on insulin signaling focuses on these tissues.

When queens and wannabe queens of the species Harpegnathos saltator gear up to reproduce, a part of what’s called the insulin signaling pathway gets blocked, slowing aging, the researchers ...

(Medical Xpress) -- Researchers at the Stanford University School of Medicine have identified a molecular signaling pathway that drives the growth and maturation of young human beta cells &#151 ...

Analysis of individuals with rare, molecularly defined defects in the signaling pathway activated by the hormone insulin (which controls blood glucose levels) has provided new insight that might ...

In 2021, a research team discovered the insulin-inhibitory receptor 'Inceptor' and its role as a suppressor of the insulin signaling pathway. Now, the researchers have unlocked another, even more ...

More information: Michael Turewicz et al, Temporal phosphoproteomics reveals circuitry of phased propagation in insulin ...

We investigated the role of insulin-Akt-FOXO1 signaling pathway in CYP7A1 transcriptional regulation since we found putative insulin-response elements, FOXO1 binding sequences, in both rat and ...

The insulin/IGF signaling pathway is a key pathway in the regulation of energy metabolism and cell survival. Therefore, we suspected that SARS-CoV-2 affects this signaling pathway to cause ...

Leptin and Insulin Resistance Pathway Convergence. At the cellular level, leptin signaling intersects with insulin pathways in pancreatic β-cells.