Just days before the deadline to turn in signatures, a Cole County judge hears arguments over whether 92,000 signatures ...

According to the Missouri State Highway Patrol, there is a multi-vehicle crash on Nash Road/MO-AB south of County Road 217.

In Williamson County, Southern Illinois Healthcare is expanding access to advanced cancer clinical trials, including a global ...

PEACH ORCHARD, Mo. (KFVS) - President Donald Trump says money is on the way to U.S. farmers, hurt by the trade war with China ...

(Gray News) - The Powerball jackpot reached $875 million before Monday night’s drawing. If won, it would be the seventh ...

HARRISBURG, Ill. (KFVS) - A nonprofit program in southern Illinois will host two free community events to celebrate Christmas ...

Three Fredericktown men were injured in a single-vehicle crash in Madison County, Missouri, on Sunday evening Chris Wuestling ...

SOUTHEAST MISSOURI (KFVS) - A Heartland holiday tradition is marking two decades. The Christmas Country Church Tour will take ...

PADUCAH, Ky. (KFVS) - Two Metropolis women and a Paducah man were arrested in connection with a robbery investigation. Quante ...

CARBONDALE, Ill. (KFVS) - Two juveniles were arrested in connection with a reported vehicle burglary. According to the ...

Jeff Cunningham sat down with Dr. Brad Hodson, SEMO president, to discuss enrollment, international students and more.

The ISA is now planning to partner with the Franklin County Sheriff’s Office in a pilot program that involves a partnership ...