Structural studies of a mitochondrial ATP synthase illustrate the basis for the diversity of its membrane-shaping properties.

Now, using the fully solved structure of F1Fo, Sazanov and his group can describe how the pore forms in F1Fo-ATP synthase: When Calcium binds in the F1 subunit, a large conformational change is ...

With no known treatments for mitochondrial diseases or ATP synthase deficiency, the use of muropeptides as an ATP agonist is a significant discovery. Recent advances in the understanding of the ...

Adenosine triphosphate (ATP) is a key molecule which upon hydrolysis provides energy to facilitate a variety of cellular processes that are essential for life.

ATP synthase CF1 α subunit protein is a key enzyme for energy metabolism in plant kingdom, and plays an important role in multiple cell processes. In this study, the complete atpA gene (accession no.

ATP, the fuel of life, is produced in mitochondria of living cells by a molecular machine, the ATP synthase. Researchers have isolated the machines from four fungal species, compared their ...

Ribonucleotide reductase subunit-2 (RRM2) and thymidylate synthase (TS) to predict shorter survival in patients (pts) with resected stage I-III non-small cell lung cancer (NSCLC).

Since raising the activity of ATP synthase may boost mitochondrial respiration and energy production, a chemical agonist of ATP synthase would have high therapeutic potential in this regard.