Mitochondria are cell organelles surrounded by a double membrane. In addition to numerous essential functions in the ...

Analysis of whole brain protein extracts from 8.5–10-month-old mice revealed a decrease in the levels of the NADH-ubiquinone oxidoreductase 30-kDa subunit (OxPhos complex I) and of the ATP ...

P5CS-containing mitochondria lacked the MICOS complex component MIC60 and ATP synthase subunit ATP5I. Lack of OPA1 disrupted the cristae but did not prevent proline biosynthesis.

GlobalData’s report assesses the drugs in the Proteasome Subunit Beta Type 8 pipeline by therapy areas, indications, stages, MoA, RoA, molecule type and the key players in the development pipeline.

Currently, ATP Synthase is a drug target for various infectious diseases, cardiovascular diseases and cancer. For instance, bedaquiline (Sirturo) is an FDA approved drug that targets bacterial ATP ...

ATP synthase is one of such protein complexes, located in the inner membrane. ATP synthase produces the bulk of cellular energy and can therefore be considered as the turbine of cellular power plants.

All the latest science news on atp synthase from Phys.org. Find the latest news, advancements, and breakthroughs.

Exome analysis revealed a de novo heterozygous variant in ATP5F1B, which encodes the β subunit of mitochondrial ATP synthase (also called complex V).

With no known treatments for mitochondrial diseases or ATP synthase deficiency, the use of muropeptides as an ATP agonist is a significant discovery. Recent advances in the understanding of the ...

Since raising the activity of ATP synthase may boost mitochondrial respiration and energy production, a chemical agonist of ATP synthase would have high therapeutic potential in this regard.