A cutting-edge mouse study reveals that tirzepatide, the dual GLP-1/GIP drug already hailed for impressive weight loss, does more than trim fat: it slashes the growth of obesity-linked breast tumors.

This discovery not only unveils a novel mechanism by which BAT influences liver metabolism but also highlights miR-206-3p as a potential therapeutic ...

Obesity is causally linked with the development of cardiovascular disorders. Accumulating evidence indicates that cardiovascular disease is the collateral damage of obesity-driven adipose tissue ...

In the lean, healthy state, adipose tissue (AT) has critical roles in maintaining organismal homeostasis. Paramount among the various roles of AT is the regulation of whole body metabolism. While ...

The correlation between red blood cell folate levels and visceral adipose tissue mass was examined, with stratification factors adjusted for a spectrum of covariates encompassing age, sex, poverty ...

Perivascular adipose tissue (PVAT) is of paramount importance as it closely surrounds blood vessels and releases a variety of active substances through paracrine and autocrine mechanisms (1, 2). PVAT ...

Prostaglandin E2 (PGE2), a crucial lipid mediator governing tissue stem cell expansion and regeneration, represents a promising therapeutic target for tissue repair. Based on the premise that ...

In an upcoming research project, adipose-derived stem cells and vascular endothelial cells will be cultured on a three-dimensional tissue chip to study their angiogenic potential.

imageimageSystemic signals from distant tissues can influence tumor cell growth. This study reveals an inter-organ signaling loop in Drosophila that involves the adipose tissue-derived Toll ligand ...