Left: The 23 pairs of chromosomes of cells in which autophagy is functioning look normal and healthy with no structural or numerical aberrations (each color represents a unique chromosome pair).

Autophagy and apoptosis control the turnover of organelles and proteins within cells, and of cells within organisms, respectively. It is now clear that these processes often occur sequentially ...

A University of Colorado Cancer Center study published today in the journal Developmental Cell pinpoints a molecule that links autophagy and apoptosis, namely a transcription factor called FOXO3a.

Both apoptosis and autophagy are crucial mechanisms regulating cell survival and homeostasis. 17, 19, 35 Although modulation of autophagy by apoptotic signaling pathways has been studied ...

Opening an autophagy window as the apoptosis door starts to close. ScienceDaily . Retrieved June 2, 2025 from www.sciencedaily.com / releases / 2020 / 09 / 200924101927.htm ...

A recent study published in Genes & Diseases reveals a novel role of XPR1 in promoting ovarian cancer growth by regulating ...

WIKIMEDIA, NATIONAL INSTITUTES OF HEALTH Cancer cells in the throes of death, being ripped apart from the inside by apoptosis, can evidently survive and piece themselves back together. A study ...

LIVE OR DIE: In breast cancer cells expressing estrogen receptor-α (ER-α), the inhibition of the autophagy gene ATG7 (top panel) allows an apoptosis transcription factor, IRF1, to lead the cancer cell ...

Identify the effects of PIKfyve inhibition on autophagic flux and tumor growth in pancreatic cancer. Analyze the efficacy of combining PIKfyve inhibitors with RAS or ERK-MAPK pathway inhibitors in ...

Autophagy and Cancer . Autophagy has both tumor-suppressing and tumor-supporting roles, depending on the tumor’s stage and environment. In early stages, ...

Jia-Yu Wu, Bing Han, Ting Yang, Lu Zheng, Yi-Xin Guo, Jia-Yao Li, Xiao-Yu Guo, Huan-Huan Yin, Ru-Jia Xie, CHOP aggravates hepatocyte apoptosis upon endoplasmic reticulum stress by downregulating ...