Three-dimensional (3D) cancer models have emerged as pivotal tools in oncology research, offering a more accurate representation of tumor biology compared ...

The Chan Zuckerberg Initiative (CZI) reports its latest AI model aimed at helping researchers better understand how cells ...

Tumor necrosis factor α-induced protein 3-interacting protein 1 (TNIP1) is a ubiquitin-binding protein that is widely expressed, but its function in breast cancer cells remains unknown.

Blood-based circulating tumor DNA (ctDNA) testing has proven to be insufficient for detecting KRAS mutations in patients with ...

It is well known that apoptosis is an actively mediated cell suicide process. In contrast, necrosis, a morphologically distinct form of cell death, has traditionally been regarded as passive and ...

Recombinant proteins are critical for modern therapeutics and diagnostics, with Chinese hamster ovary (CHO) cells serving as the primary production platform. However, environmental and chemical ...

In particular, how heat-resistant cancer cells regulate necrosis has received little scientific attention, limiting hyperthermia's potential as a standard cancer treatment.

A new study argues that necrosis — the uncontrolled “bursting” of damaged cells — may be a major upstream driver of everything from cancer and heart attacks to kidney disease and even aging itself.

The process of necrosis, a form of cell death, may represent one of the most promising ways to change the course of human aging, disease and even space travel, according to a new study by ...

Other experiments showed that slowing down the rate of cell division suppressed cancer independently of other known resistance mechanisms, such as apoptosis and immune clearance, indicating that ...

Cancer cells resist chemotherapy in low-glucose environments by conserving pyrimidine nucleotides, reducing drug effectiveness and blocking cell death. A study uncovers how cancer cells adapt to ...

Our bodies divest themselves of 60 billion cells every day through a natural process of cell culling and turnover called apoptosis.