Most B cells in peripheral lymphoid tissues are produced in adult bone marrow and are referred to as B-2 cells. A minor B-cell population, known as the B-1-cell population, that is mainly involved ...

In this Review, Nicole Baumgarth describes the development and functions of B-1 cells. These innate-like B cells serve as the major source of natural antibody in mice, and can have important roles ...

B-1 cells in mice are a type of B cell that produces natural antibodies, which are antibodies produced without infection. Such natural antibodies can aid in producing tolerance, the process where the ...

These mysterious cells, known as B-1 cells, were first discovered in mice in the 1980s, according to a 2018 review in The Journal of Immunology.These cells arise early in mouse development, in the ...

B-1 cells in mice are a type of B cell that produces natural antibodies, which are antibodies produced without infection. Such natural antibodies can aid in producing tolerance, ...

B-1 cells are a self-reactive sub-class of B cells that continuously produce antibodies that can react against the body's own substances. However, they are beneficial rather than harmful, ...

The grants, totaling $4.2 million, will fund important research projects in the Center for Immunobiology focused on B cells and the antibodies they produce, according to university officials.

B-1 cells are a self-reactive sub-class of B cells that continuously produce antibodies that can react against the body's own substances. However, they are beneficial rather than harmful, ...

At the surface, the immune response to a flu virus is simple. Some cells recognize the pathogen and send a signal to the immune system, and immune cells produce a potentially lifesaving antibody ...

Locke FL, Ghobadi A, Jacobson CA, et al. Long-term safety and activity of axicabtagene ciloleucel in refractory large B-cell lymphoma (ZUMA-1): a single-arm, multicentre, phase 1–2 trial.

This aspect of its pathogenesis places type 1 diabetes in marked contrast to spontaneous autoimmune diabetes in NOD mice, which has been claimed to be B-cell–dependent. 9–11 Although we do not ...