But because CTP synthase hasn’t fully made the transition to structural protein in billions of years of evolution, these filaments are probably as far as it will go.

Nature - Erratum: CTP synthase 1 deficiency in humans reveals its central role in lymphocyte proliferation Skip to main content Thank you for visiting nature.com.

CTPS1 is one of two forms of CTP synthase enzymes produced in mammalian cells (the other being CTPS2); both enzymes enable the production of cytidine nucleotide triphosphate (CTP), a nucleotide ...

These preclinical programs — AMPKβ2 (AMP-activated protein kinase, β2 subunit), CTPS1 (CTP synthase 1), Cbl-b (Cbl proto-oncogene B), and WRN (Werner syndrome ATP-dependent helicase ...

Nimbus Therapeutics, a biotechnology company designing breakthrough medicines through structure-based drug discovery and development, today published ...

In animal experiments of blood vessel injury, researchers found that a compound called a CTP synthase inhibitor successfully blocked smooth muscle growth and either promoted or didn't interfere ...

Nimbus Clotho Inc. has identified CTP synthase 1 (CTPS1) inhibitors reported to be useful for the treatment of psoriasis, lichen planus, lupus nephritis, systemic lupus erythematosus, multiple ...

In 2010, cytidine triphosphate synthase (CTPS) was independently discovered by three research groups. ... (CTP) that can form filamentous structures called cytoophidia.

In animal experiments of blood vessel injury, researchers found that a compound called a CTP synthase inhibitor successfully blocked smooth muscle growth and either promoted or didn't interfere ...