Molecular glues, tiny molecules that connect one protein to another, are promising targets for pharmaceutical research. By ...

PCAF acetylates RAD51, leading to RAD51 dissociation from chromatin and degradation. This highlights a regulatory role for ...

SMC (structural maintenance of chromosomes) protein complexes are ring-shaped molecular motors essential for genome folding. Despite recent progress, the detailed molecu ...

G protein-coupled receptors (GPCRs) are a large family of membrane receptors displaying seven transmembrane helical domains that can couple to heterotrimeric G proteins (guanine nucleotide-binding ...

Learn more about the research of Mayo Clinic's Gene Editing and Cellular Engineering Laboratory led by David (Chun-Wei) D.