The ability of protein kinases to transfer a phosphate group to target proteins plays an important role in many cellular ...

This innovative software, CRISPRware, optimizes guide RNA design for genome editing, supporting research on genetic disorders ...

A Ph.D. student in biomolecular engineering at the University of California, Santa Cruz, has built a software program ...

In vivo base editing enables precise, single-nucleotide changes to DNA without double-strand breaks. A recent application in ...

Tris(1,3-dichloro-2-propyl)phosphate (TDCIPP) is a high-production-volume organophosphate flame retardant (OPFR) that induces epiboly defects during zebrafish embryogenesis, leading to the disruption ...

Introduction Idiopathic pulmonary fibrosis (IPF) is characterised by accumulation of fibroblasts and myofibroblasts and deposition of extracellular matrix proteins. Sphingosine-1-phosphate (S1P) ...

Impact of Mixture Effects between Emerging Organic Contaminants on Cytotoxicity: A Systems Biological Understanding of Synergism between Tris (1,3-dichloro-2-propyl)phosphate and Triphenyl Phosphate ...

Baby KJ had been diagnosed with carbamoyl phosphate synthetase 1 (CPS1) deficiency shortly after his birth in August 2024. In a mere six months, scientists across academia and industry developed and ...

It begins with the formation of carbamyl phosphate from ammonia by carbamyl phosphate synthetase. Carbamyl phosphate is added to ornithine to form citrulline by ornithine transcarbamylase.