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Unfortunately, clinical Mycobacterium tuberculosis strains rapidly become resistant to bedaquiline, predominantly by overexpression of MmpL5. The proteins MmpL5 and MmpL4 are efflux transporters, ...
In a recent study, researchers have uncovered the biological trigger behind the dangerous immune-related adverse events (irAEs) that occur when the epidermal growth factor receptor (EGFR ...
In the quest to design vaccines that better help the body's immune system fight disease, scientists are always looking for more tools for their arsenal.
Celastrol, a natural compound classified as a pentacyclic triterpenoid, has demonstrated efficacy in inhibiting human colorectal cancer cells’ growth, adhesion, and metastasis through various ...
Once thought to have originated in cows and spread through dust, the surprising evolutionary story of tuberculosis reveals why it's so hard to stamp out this ancient disease, writes Carl Zimmer ...
The bacteria that cause tuberculosis (TB) may have an "on-off switch" that lets them pause and restart growth, according to a new study from the University of Surrey and the University of Oxford.
Chemists found a way to identify a complex sugar molecule in the cell walls of Mycobacterium tuberculosis, the world's deadliest pathogen. This labeling could lead to simpler, faster TB tests.
Cytokine release syndrome is caused by excessive cytokine release, and it affects immunotherapy patients and those with autoimmune diseases or severe infections.
A closely watched clinical trial testing what could be the world’s first new tuberculosis vaccine in a century has hit its enrollment target, ahead of expectations.
A panelist discusses how the comprehensive ADVANCES safety monitoring system data presented at the 2025 American Academy of Dermatology Annual Meeting (AAD 2025) revealed distinct infection risk ...
Tuberculosis was once a disease in decline, but a resurgence in cases has health officials puzzled Health Mar 23, 2025 1:38 PM EDT ...
In a new book, author John Green traces how the disease has impacted culture, geography, and even fashion over the centuries.
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