Figure 1: HCM mutant αTm structure and expression. The direct increase myofilament calcium sensitivity associated with HCM mutations in α-Tm reported here is in contrast to effects seen with HCM ...
Characteristics of the cardiac pump. Analysis of the heart as a pump has classically centered upon the relation between the filling pressure or diastolic volume (the Frank–Starling relation). It was ...
From the Cardiology Branch, National Heart Institute (requests for reprints should be addressed to Dr. Braunwald at the National Heart Institute, Bethesda, Maryland 20014). Eugene Braunwald, M.D.
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