Despite its interference with LAL assays, β-glucan displays therapeutic potential when employed as an adjuvant in monoclonal ...

The authors study how apolipoprotein L1 variants impact inflammation and lipid accumulation in macrophages. The findings will be useful for researchers investigating macrophage metabolism and ...

Abstract Summary Pharmacological enhancement of endoplasmic reticulum (ER) proteostasis is an attractive strategy to mitigate pathology linked to etiologically-diverse protein misfolding diseases.

Together with the IP-One kit for assessment of IP1, a downstream metabolite of IP3, Cisbio proposes a complete GPCR assay platform. Here we describe the HTRF kits for cAMP detection.

Antibody–siRNA conjugates (ARCs) are a type of promising drug modalities for cancer therapy. However, initial reports of ARCs present the gene knockdown effect only in limited tissues (e.g., muscles) ...

The release of a recent EMA reflection paper, aligning with FDA and WHO positions, has resulted in a renewed focus on the ...