BP1 is a key player in DNA repair and together with BRCA1 regulate selection of DNA double strand break repair mechanisms. Localization of DNA repair factors to sites of DNA damage by 53BP1 is ...

Key Points Key Points Estrogen receptors play a critical role in controlling gene activity in many tissues. When estrogen binds to ERα, the protein changes shape, forms a dimer (a molecular pair), and ...

PCR, particularly fluorescence quantitative PCR targeting MP-DNA, is highlighted as the gold ... Some children with MPP develop increased D-dimer levels, indicating a higher risk of blood clot ...

The consistency between the particle size of Sld7–Sld3–Cdc45 and the distance between Sld3CBDs in the Cdc45–MCM dimer indicated the binding manner of the Cdc45–Sld3–[Sld7] 2 –Sld3–Cdc45 off/on MCM ...

Two cigarette butts from an ashtray that had spilled onto the floor. Much of that evidence was tested for DNA. None of it matched the man serving life in prison for the crime. When the ...

On Wednesday, authorities announced DNA evidence matched the body found in the spring of 1980 on Cleveland’s East Side to a man who had gone missing nearby a month earlier. Officials identified ...

They exist as circular pieces of DNA in the nuclei of tumor cells outside chromosomes. Transcription of the amplified ecDNA genes can promote oncogenic processes, such as the increased expression ...

Urban, and Tim Liedl from LMU Munich has managed to significantly improve such tests using a cutting-edge nanotechnology called DNA origami. In DNA origami, DNA is folded—akin to the Japanese ar ...

Colossal CEO Ben Lamm said the team used DNA from a 13,000-year-old tooth and a 72,000-year-old skull to analyze the full genome of the species and create three healthy dire wolf puppies ...

THE mystery of what killed King Tutankhamun may finally be solved — after scientists unearthed groundbreaking DNA evidence. The young pharaoh's untimely death at just 18 has baffled experts for ...