Abstract Summary Pharmacological enhancement of endoplasmic reticulum (ER) proteostasis is an attractive strategy to mitigate pathology linked to etiologically-diverse protein misfolding diseases.

With a new method, researchers have captured a high-resolution metabolic “map” of how cells orchestrate glucose processing, ...

In a scientific first, researchers from Vanderbilt University and the University of California, San Diego, have generated a ...

How proteins in our cells attain their correct three-dimensional structure is crucial to their function—and to our health.

Two junior research groups at Ruhr University Bochum, Germany, have developed a drug complex that kills cancer cells in such ...

Two junior research groups at Ruhr University Bochum, Germany, have developed a drug complex that kills cancer cells in such ...

Two junior research groups at Ruhr University Bochum, Germany, have developed a drug complex that kills cancer cells in such ...

Amylyx is a high-risk biotech targeting rare diseases with strong cash reserves. Key trials soon may drive a 40% stock upside.

Sepsis-induced immune dysfunction is a major contributor to high mortality rates in septic patients. Recent findings shed light on the role of nuclear ...

A further understanding of the organelle could pave the way for better treatment of genetic and neurodegenerative diseases.