Sepsis-induced immune dysfunction is a major contributor to high mortality rates in septic patients. Recent findings shed light on the role of nuclear ...

Two junior research groups at Ruhr University Bochum, Germany, have developed a drug complex that kills cancer cells in such ...

Two junior research groups at Ruhr University Bochum, Germany, have developed a drug complex that kills cancer cells in such a clever manner that they raise a red flag as they die. They signal to the ...

Two junior research groups at Ruhr University Bochum, Germany, have developed a drug complex that kills cancer cells in such ...

Gene delivery is a key area in biomedicine, where nucleic acids are delivered into cells to treat diseases by modulating ...

Abstract Summary Pharmacological enhancement of endoplasmic reticulum (ER) proteostasis is an attractive strategy to mitigate pathology linked to etiologically-diverse protein misfolding diseases.

Human eggs are some of the most patient cells in the body, lying dormant for decades until needed. A study published in The EMBO Journal shows that the cells deliberately slow the activity of their ...

Emerging research positions TUDCA, a bile acid compound, as a promising neuroprotective agent against Alzheimer’s, ...

Turtles, known for their long lives and large bodies, rarely develop cancer, a trait that researchers now say makes them ...

A further understanding of the organelle could pave the way for better treatment of genetic and neurodegenerative diseases.

Coronary artery disease is characterized by chronic immune‐inflammation, excessive endoplasmic reticulum (ER) stress, and platelet hyperactivity; however, whether there is a signaling hub linking ...