Removing EPO signaling in mouse liver tumors leads to tumor ... the researchers studied the combinatorial effect of simultaneously blocking the EPO signaling pathway and anti-PD-1 pathway. ...

Erythropoietin possesses angiogenic activity, ... et al. Erythropoietin triggers a signaling pathway in endothelial cells and increases the thrombogenicity of their extracellular matrices in vitro.

The specific inhibition of the Epo/EpoR signaling pathway in EpoR-expressing cancers could offer a promising new approach to improve local tumor control and survival in these patients. References.

Pathogenic variants in genes of the oxygen-sensing pathway have been identified in patients with hereditary erythrocytosis, a rare hematologic disease characterized by the excessive production of ...

Stem cell researchers have discovered a critical placental niche cell and signaling pathway that prevent blood precursors from premature differentiation in the placenta, a process necessary for ...

Defeat for Erythropoietin in Infant Encephalopathy — Tide turns for presumed treatment for neonatal brain dysfunction by James Lopilato , Staff Writer, MedPage Today July 13, 2022 ...

More information: Hirokazu Yagi et al, Molecular tag for promoting N-glycan maturation in the cargo receptor-mediated secretion pathway, iScience (2024). DOI: 10.1016/j.isci.2024.111457 ...

Alnylam Pharmaceuticals, Inc. has announced the publication of new pre-clinical results in the journal Blood (doi: 10.1182/blood-2012-04-423715) that describe targeting the egg-laying nine homolog ...

Acceleron and Celgene Initiate Phase 2 Study of ACE-011 to Treat Chemotherapy-Induced Anemia Acceleron Pharma, Inc., a biopharmaceutical company developing novel therapeutics that modulate the growth ...