A groundbreaking study led by Children's Hospital Los Angeles has found a novel mechanism behind neuroblastoma progression: ...

Our study examines how RNA in extracellular vesicles (EVs) can provide insights into metabolic phenotypes related to obesity.

Abstract Cancer is a leading cause of death worldwide, and despite the introduction of new therapeutic approaches for advanced cases aimed at improving patient survival, only a subset of patients ...

Pusan National University researchers developed novel extracellular vesicle (EV)-based platform to target harmful bacteria. The tailored EVs derived from Lacticaseibacillus paracasei contain a ...

The CX3CL1-CX3CR1 axis plays a critical role in promoting tumor cell proliferation, migration, and metastasis in PDAC. Targeted delivery of small interfering RNA (siRNA) against CX3CR1 through M1 ...

Background Liver metastasis is a major cause of mortality in patients with colorectal cancer (CRC). Understanding how CRC cells influence the formation of hepatic premetastatic niches (PMNs) is ...

However, the tumor microenvironment (TME) supports tumor progression through the facilitation of immune evasion, supplying nutrients, and promoting invasive growth, metastatic processes, and treatment ...

Keywords: plant-derived extracellular vesicles, solid tumors, tumor microenvironment, antitumor therapy, precision medicine Citation: Wu H, Shi M, Meng L, Qiu J, Jiang Y, Qian D and Shen F (2025) ...

The 3D culture is currently the most promising technique used in preclinical studies for drug testing. One of the main challenges in preclinical in vitro studies is the long-term observations (over 21 ...