Understanding the regulatory function of ribosomes in modulating gene expression in human cells can provide insight about causes of gene misregulation, which can sometimes lead to human diseases.

By tethering RNA polymerase with the coupling transcription factor NusG or its paralog or version, RfaH, which threads the ...

Researchers have discovered a new function of ribosomes in human cells that may show the protein-making particle's role in destroying healthy mRNAs, the messages that decode DNA into protein.

Insights into the ribosome function from the structures of non-arrested ribosome–nascent chain complexes. Nature Chemistry , 2022; DOI: 10.1038/s41557-022-01073-1 Cite This Page : ...

A new technique reveals ribosome cooperativity, providing new insights into protein production. Researchers from Marvin Tanenbaum’s group at the Hubrecht Institute (Utrecht, Netherlands) have ...

When ribosomes produce protein in all living cells, they do so through a chemical reaction that happens so fast that scientists have been puzzled. Using large quantum mechanical calculations of ...

Proteins are absolutely essential for the survival of organisms; they carry out many functions that are critical to life. Something needs to build all of those proteins from their basic components.

Proteins are the infinitely varied chemicals that make cells work, and science has a pretty good idea how they are made. But a critical aspect underlying the machinery of protein manufacture has long ...

The main function of ribosomes is to produce proteins that are used both inside the cell and sent outside the cell. Without ribosomes, ...

Defects in ribosome biogenesis, assembly, and function of individual ribosomes are termed ribosomopathies. This article explains more about these tissue-specific phenotypic abnormalities that ...