Amino acids play a fundamental role in regulating how cells respond to drugs. These molecules, which form proteins, act like ...

G protein-coupled receptors (GPCRs) are expressed on the surface of cells and regulate a range of important functions. Because they are involved in so many sensory and physiological processes, ...

More information: Lijie Liu et al, Redox regulation of G protein oligomerization and signaling by the glutaredoxin WG1 controls grain size in rice, The EMBO Journal (2025). DOI: 10.1038/s44318-025 ...

Heterotrimeric G proteins have a crucial role as molecular switches in signal transduction pathways mediated by G-protein-coupled receptors. Extracellular stimuli activate these receptors, which ...

G-protein coupled receptors (GPCRs) play pivotal roles in signaling pathways and are the most common membrane proteins. Implicated in many diseases, they are an attractive therapeutic target.