Elevated 1-hour plasma glucose was a better predictor for prediabetes risk than fasting plasma glucose and 2-hour plasma glucose.

Initially, phosphoglucomutase (PGM1-3) catalyses the transfer of a phosphate group from the C6 position of glucose-6-phosphate (G6P) (Najjar and Pullman, 1954) to the C1 position of glucose, yielding ...

Glucose-1-phosphate thymidylyltransferase (RmlA) catalyzes the condensation of glucose-1-phosphate (G1P) with deoxy-thymidine triphosphate (dTTP) to yield dTDP-d-glucose and pyrophosphate. This is the ...

Sphingosine-1-phosphate (S1P) is a cardiovascular biomarker involved in glycocalyx preservation, linked to placentation and preeclampsia development. The study aimed to test the hypothesis that plasma ...

Among several hundreds of positive hits, they focused on one important enzyme, glucose-6-phosphate dehydrogenase (G6PD), which is a rate-limiting enzyme in the pentose-phosphate pathway (PPP), an ...

The increase in thermo-stability and reusability of the immobilized enzyme has been exploited for the production of glucose-1-phosphate, a cytostatic compound used in cardio-therapy. The ...

Glucose-6-phosphate dehydrogenase (G6PDH) catalyzes the first and rate-limiting step of the oxidative pentose phosphate pathway (OPP), converting glucose-6-phosphate (G6P) to 6-phosphogluconolactone ...

Advanced therapies have transformed the management of ulcerative colitis, but subgroups of patients do not respond to available treatments and have systemic side-effects, indicating the necessity for ...

3.3.1 Biochemical properties of glucose-6-phosphate dehydrogenase variants Four G6PD variants were purified to homogeneity using immobilized metal affinity chromatography (Supplementary Material) and ...

The sphingosine 1-phosphate (S1P) signalling pathways have important and diverse functions. S1P receptors (S1PRs) have been proposed as a therapeutic target for various diseases due to their ...

Graphical Abstract S1P (Sphingosine-1-phosphate) is an important regulator of immune cell trafficking and vascular dysfunction contributing to the development and progression of overt hypertension.