Bone growth occurs through the proliferation of specialized cells of the cartilage tissue, known as chondrocytes, on either end of a bone. This process requires the synthesis of extracellular matrix ...

The CNP-bound receptor activates a molecule, cyclic guanosine monophosphate (cGMP), which in turn activates protein kinase G (PKG) that phosphorylates a membrane ion channel. This ion channel is ...

This special issue of Current Pharmaceutical Analysis focuses on the latest advancements in polypharmacology for cancer therapy. It aims to address the challenges of drug resistance and limited ...