TPOAb and TgAb IMAs should be checked for hook effects using ~20 specimens with antibody concentrations >1,000 kIU/L and ~20 specimens with values above 10,000 kIU/L.

In a significant step toward improving targeted cancer therapy, researchers from Japan have developed a novel nanocarrier ...

A new microchip invented by Scripps Research scientists can reveal how a person's antibodies interact with viruses—using just ...

The “hook” effect is rare. The hook effect refers to a false negative (or very light line) on a pregnancy test due to extremely high hCG levels that essentially flood the test.

Antibody–siRNA conjugates (ARCs) are a type of promising drug modalities for cancer therapy. However, initial reports of ARCs present the gene knockdown effect only in limited tissues (e.g., muscles) ...

The side effects of antibodies may also differ between populations, further highlighting the need for concerted research between the public and private sectors 24.

These findings highlight the dual roles of antioxidants in cancer. Their impact depends on cancer type, stage, and genetic ...

The hook effect describes the detection of erroneously low analyte levels in an immunoassay as a consequence of extremely high concentrations of antigen (e.g. calcitonin), which affect the binding ...

Antibody-specific treatment of the well-characterized autoimmune dysfunction is not yet possible. The cause of MG is unknown apart from in thymoma cases, where the tumor initiates specific ...

A doctor may recommend inducing labor to avoid complications for the pregnant person or fetus. Read about the reasons for induction, methods, and risks.