Researchers are working to launch a first-in-human clinical trial to test the approach in patients with cancer who develop ...

Subsequently, the same group of researchers showed that the signaling of Rac1 would be down regulated in skeletal muscles of rodents that are insulin-resistant 67. Another protein located in the ...

Signaling pathways play an important role in the cell's response to its environment. Signaling pathways are often represented as directed graphs, which are not adequate for modeling reactions such as ...

In obesity, adipose tissue macrophages are polarized into pro-inflammatory M1 macrophages and secrete many pro-inflammatory cytokines capable of impairing insulin signaling, therefore promoting the ...

This suggests that oxytocin may trigger insulin production through a separate, receptor-dependent pathway involving the hormone GLP-1.