Although the heterotrimeric receptors for interleukin-2 (IL-2) and IL-15 have two subunits in common, these cytokines have contrasting roles in adaptive immune responses. Understanding the biology ...

“We have now come one step closer to a detailed understanding of how the IL-2 cytokine works,” de Paula said. “It is the first time that anyone has managed to observe a transient state of IL-2 ...