Interleukin-2 (IL-2) inhibitors are immunosuppressive agents that block the activity of IL-2, a cytokine involved in the activation and proliferation ...

Interleukin-2 inhibits FMS-like tyrosine kinase 3 receptor ligand (flt3L)-dependent development and function of conventional and plasmacytoid dendritic cells Annie W. Lau-Kilby, Cosima C. Kretz, ...

REZOLVE-AD, the phase 2b study, is set to investigate the efficacy and safety of rezpegaldesleukin, a first-in-class interleukin-2 receptor agonist that proliferates and activates regulatory T ...

On Tuesday, Coya Therapeutics, Inc. (NASDAQ:COYA) released results from the placebo-controlled Phase 2 trial of LD IL-2 in patients with mild to moderate Alzheimer’s Disease. The data was shared ...

GlobalData’s report assesses the drugs in the Interleukin 2 Receptor Subunit Beta pipeline by therapy areas, indications, stages, MoA, RoA, molecule type and the key players in the development ...

The measurement of soluble interleukin-2 receptor (sIL-2R) levels in serum or plasma in adults has become a valuable tool for clinicians to assess immune function in vivo as part of the ...

Wang KS, Frank DA, Ritz J. Interleukin-2 enhances the response of natural killer cells to interleukin-12 through up-regulation of the interleukin-12 receptor and STAT4.

Soluble interleukin-2 receptors were assayed with an enzyme-linked immunosorbent assay (ELISA) (Gen Zyme) in the serum of patients and control subjects. Microtiter plates were precoated with a ...