Abstract: A dynamical model is proposed in this paper for describing the key quantities of mitochondrial metabolism. Mitochondria are very important cell organelles, because they take part in the ...

In the prebiotic network, we found that pyruvate and acetate exhibit remarkable stability and accumulate in substantial quantities, thereby feeding the TCA cycle through the production of citrate. In ...

Explorative analyses of 48 h urine, both by 1H NMR and LC–MS metabolomic platforms, demonstrated higher urinary excretion of tricarboxylic acid (TCA) cycle intermediates citric acid and succinic acid ...

The fungus Talaromyces verruculosus can produce the chemical erythro-isocitric acid, which has received little attention on the market to date, directly from cheap plant waste and thus make it ...

Citric acid — a compound that occurs naturally in fruits like lemons and pineapples — appears in everything from cleaning products to dietary supplements to Doritos. But as a professional ...

The tricarboxylic acid (TCA) cycle is the central metabolic pathway responsible for the oxidation of acetyl-CoA into two molecules of CO 2 with the concomitant reduction of NAD (P) and quinone (Figure ...

We tested the hypothesis that the recently identified, pervasive cerebral deficiency of pantothenate (vitamin B5) in sAD, might undermine brain energy metabolism by impairing levels of tricarboxylic ...

The prostate is metabolically unique: it produces high levels of citrate for secretion via a truncated tricarboxylic acid (TCA) cycle to maintain male fertility. In prostate cancer (PCa), this ...

The Krebs cycle may be like a busy roundabout, as vehicles whizz in and out from different junctions Transformer: The deep chemistry of life and death Nick Lane Profile Books   IF WE want to ...