Abstract Autophagy is a catabolic recycling pathway triggered by various intra- or extracellular stimuli that is conserved from yeast to mammals. During autophagy, diverse cytosolic constituents are ...

In addition to its role in lysophagy, the E3‐like conjugation complex has been shown to regulate the unconventional LC3 lipidation onto damaged lysosomal membranes, independent of the autophagy ...

Autophagy-related LC3 accumulation stimulates necroptosis through direct interaction of LC3 with RIPK1 and RIPK3 in hypoxic cardiomyocytes. Schematic diagram on the proposed process where impaired ...

The results highlight how the unique combination of transducer- and system design, in combination with resistive sensing enables the rapid, robust and accurate detection of the LC3 protein, reporting ...

Autophagy Lab, Molecular Biology and Genetics Unit, Jawaharlal Nehru Centre for Advanced Scientific Research, Bengaluru, India Growing amount of evidence in the last two decades highlight that ...

However, the regulation of endothelial phenotypes by SS remains not fully elucidated. Macroautophagy (hereafter referred to as autophagy) is a major intracellular recycling system. Under basal ...

Here, we used DyLight488-labeled anti-LC3 antibodies to label endogenous LC3 present on organelles isolated from murine liver tissue prior to CE-LIF analysis. We evaluated the ability of this method ...