Lipoprotein apheresis involves the extracorporeal removal of LDL and lipoprotein(a) particles from whole blood or plasma by adsorption, precipitation or differential filtration. Used repetitively ...

The authors study how apolipoprotein L1 variants impact inflammation and lipid accumulation in macrophages. The findings will be useful for researchers investigating macrophage metabolism and ...

BACKGROUND: Primary aldosteronism (PA), an overt form of renin-independent aldosterone production, leads to a disproportionately high rate of major adverse cardiovascular events (MACEs). Mounting ...

Katherine Wilemon from the Family Heart Foundation discusses the importance of detecting high lipoprotein(a) levels to prevent adverse health consequences.

Excited by strong phase II data, Novartis is exercising its option to license Akcea Therapeutics’ TQJ230, a treatment to reduce the risk of cardiovascular disease in people living with elevated ...

Amgen has reported encouraging mid-stage results for its olpasiran candidate for reducing lipoprotein(a) – a risk factor for atherosclerotic cardiovascular disease – and now plans to move ...

Lipoproteins articles from across Nature Portfolio Lipoproteins are large spherical complexes that consist of lipids and proteins. The hydrophobic core consists of triglycerides and a hydrophobic ...

High cholesterol typically doesn't cause any symptoms. In the majority of cases, the only symptoms it may cause are emergency events.