Previously known as primary amyloidosis, systemic amyloid light chain (AL) amyloidosis is the most common form of systemic amyloidosis in developed countries. Although occasionally localized and ...

Management of cardiac amyloidosis requires a twofold approach: Management of cardiac-related symptoms with appropriate medical treatment, general supportive care and organ transplantation in ...

Consequently, any potential impact would be localized and limited, not extending to Egypt. He elaborated: “According to international standards, a radius of 3 to 5 kilometers around major nuclear ...

AstraZeneca has clearly made the rare disease transthyretin amyloidosis (ATTR) a key component of its rare disease pipeline, licensing a second drug candidate in the space of a couple of months ...

Four years after getting the first drug approved by the FDA to treat rare disease hereditary ATTR amyloidosis, Alnylam has got the go-ahead for a second – Amvuttra – which has a simpler, more ...

Professor John McGrath, from King's College London, studied a large Brazilian family who suffered from a condition called primary localised cutaneous amyloidosis (PLCA). It affects several thousand ...

Figure 3: Effect of RAGE blockade on systemic amyloidosis in a mouse model: plasma SAA levels, splenic NF-κB activation and expression of transcripts for cell stress markers.

Occasional neck pain is often due to poor posture, normal wear, or overuse. Learn about neck pain causes, treatment, and home remedies.

Discussion with the article authors Join a complimentary virtual symposium on next steps for personalized nucleic acid nanomedicines.

XD is considered a localized ECD (50). Cutaneous manifestations of ECD consist of eyelid and periorbital xanthelasmas or other XD-like lesions; still, long-bone osteosclerosis and cardiovascular ...

Amyloidosis is the most significant complication of FMF, leading to end stage renal disease (ESRD). Recently the gene (MEFV) causing this disease was cloned and more than 18 mutations have been ...

OBJECTIVE: To determine whether patients with myocardial amyloidosis due either to AL (primary) amyloid or familial amyloid have distinguishing echocardiographic or electrocardiographic features; and ...