Most dangerous bacteria are attacked by macrophages. The macrophage engulfs bacteria and ... He and his colleagues have studied mycobacteria and macrophages directly through a confocal microscope.

A microscope image of S. pneumoniae bacteria (green) being consumed by a macrophage in a mouse Hong Li, Ph.D. / NIEHS Follow-up tests were conducted in human cells in the lab.

He infected a cell with MRSA under a microscope and inserted a dye that would glow in the presence of ROS. Mitochondria in the infected cell began to glow, as did the macrophage when the bacteria ...

Most dangerous bacteria are attacked by macrophages. The macrophage engulfs bacteria and immediately traps them in a separate cell compartment, or vesicle. This vesicle is called a phagosome and ...

The researchers also discovered that when these cells, called macrophages, eat live bacteria it triggers an inflammation response. But when they eat dead bacteria it doesn’t. “When phagocytic cells ...

The team found that, unlike live bacteria, dead bacteria contained 3′,5′-cyclic adenosine monophosphate (cAMP) and released a byproduct of this metabolite upon phagocytosis by macrophages. This in ...

When the macrophages were exposed to live bacteria, the researchers observed that they triggered strong inflammatory responses characterized by high levels of TNF-α, IL-6, and IL-1β.

Now, Vanderbilt researchers led by postdoctoral fellow Andrew Monteith, PhD, have discovered that NETs boost the bacterial killing power of another type of immune cell: macrophages.

Investigating how CFTR mutation affected the ability of immune cells called macrophages to fight off bacteria, the researchers found that, in CF, lung macrophages can’t properly use zinc as an ...

Macrophages destroy bacteria by engulfing them in intracellular compartments, which they then acidify to kill or neutralize the bacteria. However, some pathogenic bacteria, such as Salmonella ...

Macrophages engulf invading bacteria and fungi and then kill them in the phagosome. How exactly this is achieved is still a matter of debate, as undoubtedly it is not only a single mechanism.

Immune cells that eat bacteria in the body don’t stash them in specialized compartments as once thought, but turn them into critical nutrients that build proteins, create energy and keep the cells ...