Rotblat B, Southwell AL, Ehrnhoefer DE, Skotte NH, Metzler M, Franciosi S, et al. HACE1 reduces oxidative stress and mutant Huntingtin toxicity by promoting the NRF2 response.

Small ubiquitin-like modifiers (SUMO) and ubiquitin are frequent post-translational modifications of proteins that play pivotal roles in all cellular processes. We previously reported mass ...

Huntington’s disease (HD) is caused by an expansion mutation of a CAG repeat in exon 1 of the huntingtin (HTT) gene, that encodes an expanded polyglutamine tract in the HTT protein. HD is ...

Since the first running of the Melbourne Cup in 1861 there have been over 150 winners of Australia’s premier horse race. Some of Australia’s greatest race horses have run and won the Melbourne Cup ...

Yesterday saw the official release of Death Stranding 2: On the Beach, the highly anticipated sequel to Kojima Productions' debut title, written, directed, and produced by, you guessed it, Hideo ...

View Composition with figures and house by Wiliam Skotte Olsen on artnet. Browse upcoming and past auction lots by Wiliam Skotte Olsen.

— Christian Skotte, The 74 That’s when the partnership between Stacker and The74 clicked. Stacker saw The 74 not just as another contributor, but as a bold, mission-driven newsroom that could help set ...