Scientists at the University of California, Irvine, have discovered that nuclear speckles, a membraneless organelle within the nucleus, serve as central hubs for pre-mRNA 3′ end processing. This ...

In a recent article, he showed that when genes are preferentially positioned near speckles, mRNA splicing is significantly more efficient. 4 “It’s huge for the RNA processing field, because now it ...

image: Markers for SON (red; left image) and SRRM2/SC35 (green; center image) highlight where nuclear speckles are located (right image) in relation to the cell's DNA (blue).

With GSS, a given selectable marker, usually a phenotypic trait, is linked to sex to aid in the sorting process. Some GSS could include more than one marker. The VIENNA 8 strain of the Mediterranean ...

The protein acts as a matchmaker, bringing together speckles and DNA containing these target genes. When the speckles and genes get close, the level of transcription of the genes jumps significantly.