One injection could do the trick, but if the numbers don’t drop like they should, you might have more injections. Surgery. If methotrexate therapy doesn’t work, surgery is the next step.

Data analysis included 194 patients with 224 uveitic eyes. The primary endpoint was change in CST from baseline to 12 weeks. All three treatments led to statistically significant reductions, led ...

A randomized trial comparing methotrexate injections, infusion, or both for primary rhegmatogenous retinal detachment repair will begin enrolling patients before the end of the year, Franklin added.

A total of 152 participants were randomized 2:1 to run-in and treatment periods with oral methotrexate (15 mg/week) or placebo, followed by a 52-week treatment period of KRYSTEXXA (8-mg bi-weekly ...