Further, the study shows BRCA2-deficient cells retain PARP1 when exposed to PARP inhibitors. This study presents significant new findings that could have a profound impact on the development of ...

A couple facing a terminal multiple myeloma diagnosis finds renewed hope through innovative immunotherapy, transforming blood cancer treatment.

The immune system plays a key role in detecting and destroying cancer cells. Cancer immunotherapy works by programming immune cells to recognize and eliminate cancer cells.

A new study shows how an anticancer drug triggers an “outside in” signal that gets it sucked into a cancer cell. The work, published Jan. 29 in Nature Communications, reveals a new signaling mechanism ...

"We have found a new mechanism by which tumor cells evade the immune system. In further studies, we will now examine IRGQ's influence on other types of cancer," emphasizes Đikić.

“We have found a new mechanism by which tumor cells evade the immune system. In further studies, we will now examine IRGQ’s influence on other types of cancer,” emphasizes Đikić.

Of these four types, drug resistance mutations, otherwise known as canonical drug resistance mutations, are genetic changes in the cancer cell that lead to the drug being less effective.

Drosophila study discovers mechanism that could control longevity, cancer cell production by Lorena Anderson, University of California - Merced Editors' notes ...

Conventional cancer drugs work by triggering apoptosis, that is programmed cell death, in tumor cells. However, tumor cells have the ability to develop strategies to escape apoptosis, rendering ...

Researchers have, for the first time, observed a mechanism used by cancer cells to resist the effects of chemotherapy. The findings could be used to develop targeted drugs to help override it and ...

Human tumours in mice have been eradicated by human immune cells that were genetically engineered to boost their anticancer activity. So far, engineered immune cells have proved ineffective ...

Researchers from Karolinska Institutet have discovered a new molecular mechanism by which cancer cells safeguard themselves from oncogene-induced replication stress and propose a strategy to ...