tuberculosis, this tag showed up in the outer layer of the cell wall. When the researchers exposed the label to Mycobacterium smegmatis, a related bacterium that does not cause disease and does not ...

Macrophages infected with Mycobacterium tuberculosis were fixed and imaged at four hours and 72 h postinfection. (Scale bar, 4 μm.) LAM labeling with oxaziridines persists for up to 72 h.

The subject of Aldridge’s research is the bacterium Mycobacterium tuberculosis, the causative agent of tuberculosis. In 2023, TB made 10.8 million people sick and killed around 1.25 million people.

TMC207 inhibits the proton pump of mycobacterial ATP synthase, a critical enzyme in the synthesis of ATP for Mycobacterium tuberculosis. Resistance is achieved through mutations at position 63 or ...