First-ever clinical trial exclusively conducted among people with hard-to-treat form of tuberculosis known as pre-extensively drug-resistant TB shows many patients benefit from shorter, simpler ...

A vaccine protects more than 100 million infants each year from severe tuberculosis (TB), including the fatal brain swelling it can cause in babies and toddlers.

A vaccine protects more than 100 million infants each year from severe tuberculosis (TB), including the fatal brain swelling ...

The design and optimization of a surface plasmon resonance (SPR) biosensor for very sensitive detection of Mycobacterium tuberculosis are presented in this work. Using the transfer matrix method (TMM) ...

Growing evidence points to the modification of LM and LAM with discrete covalent substituents as a strategy used by these bacteria to modulate their biological activities. One such substituent, ...

The high-temperature requirement A (HtrA) family of serine proteases has been shown to play an important role in the environmental and cellular stress damage control system in Escherichia coli.

This work describes the most extensive discovery and functional characterization of small regulatory RNAs (sRNAs) in Mycobacterium tuberculosis to date. We comprehensively define the sRNAs expressed ...

Researchers conducted a retrospective cohort study at a tuberculosis referral hospital in East London, South Africa, comparing patients aged ≥13 years with confirmed phenotypic bedaquiline-resistant ...

The genetic bases for signature phenotypes of Mycobacterium tuberculosis, including acid fast staining, virulence, and susceptibility to tuberculosis (TB)-specific drugs were unknown before the ...