Ferroptosis begins with phospholipid peroxidation, leading to membrane damage rupture and cell death. Although research has surged, the intracellular site for ferroptosis initiation remains uncertain.

Exosomes derived from PEDF modified adipose-derived mesenchymal stem cells ameliorate cerebral ischemia-reperfusion injury by regulation of autophagy and apoptosis.

Research Progress on Ferroptosis Mechanism in Endometrial Cancer. Journal of Biosciences and Medicines, 13, 65-74. doi: 10.4236/jbm.2025.137005 . Endometrial Cancer (EC) is an epithelial malignant ...

Heterogeneous Hippo pathway (YAP/TAZ) activation in lung adenocarcinoma drives tumor progression by enabling ferroptosis ...

These findings highlight the dual roles of antioxidants in cancer. Their impact depends on cancer type, stage, and genetic ...

Fat isn’t just a guilty pleasure — it’s cancer’s secret weapon. New research from UT Southwestern Medical Center is shedding light on why this is the case.

This resistance involves two distinct cell death types: necrosis, which occurs rapidly through direct physical damage to cell membranes, and apoptosis, a slower, programmed cell death that happens ...

Learn how researchers link IBD to ferroptosis, a form of cell death driven by lipid ROS, offering new hope for targeted treatments in Crohn’s and colitis.

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