Recent research has identified a series of previously unrecognized regulated cell death modalities beyond apoptosis, including necroptosis, parthanatos, ferroptosis and oxytosis. Several genetic ...

Up to the 1980s, cell death caused by drugs, chemicals, and other pathophysiologies was primarily considered necrosis. This view radically changed with the discovery of apoptosis and its specific ...

In this brief description of cell death modalities, we draw parallels between the apoptosis, pyroptosis, necroptosis, and ferroptosis, and conclude that ferroptosis does not share characteristics ...

Furthermore, labile iron–induced ferroptosis involved a unique set of genes that were also involved in apoptosis and necrosis.

Heart Health and Ferroptosis Dynamic How does ferroptosis affect the cells in the heart? Researchers found six fundamental forms of cell death in the cardiovascular system: Apoptosis Necroptosis ...

As with necrosis, the cells and their organelles swell up and then the outer membrane ruptures. Necroptosis is a handy backup mechanism because some infectious agents can disable apoptosis.

As with necrosis, the cells and their organelles swell up and then the outer membrane ruptures. Necroptosis is a handy backup mechanism because some infectious agents can disable apoptosis.

Ferroptosis is a recently recognized form of regulated necrosis. Up until now, this form of cell death has only been thought to be a possible therapeutic approach to treat tumour cells. Yet ...

Necrosis and Apoptosis are crucial for multicellular homeostasis, but it also plays an ill-fated role in human disorders.

However, tumor cells have the ability to develop strategies to escape apoptosis, rendering the drugs ineffective. A research team now describes a new mechanism of action that kills cancer cells ...

A high number of neutrophils and the presence of genetic signals of ferroptosis were associated with pathological evidence of necrosis and predicted poor survival in patients." ...