Three-dimensional (3D) imaging is essential for investigating cellular structure and dynamics. Traditional optical methods ...

In the 20 th century, light microscopes relied solely on focusing light in space for the separation (=resolution) of adjacent tiny features. Either they focused the illumination light as sharply ...

Optical microscopes are still second to none when it comes to analyzing biological samples. However, their low resolution, improved only in recent years in STED microscopes, continues to be a problem.

A team has made a major breakthrough in the field of three-dimensional (3D) imaging of large-scale biological tissues. They ...

“The resolution of the standard optical microscope is basically limited by the diffraction barrier of light, which restricts the resolution to 200–300 nm for visible light,” explains Mark Schüttpelz, ...

Optical microscope without lenses produces high-resolution 3-D images on a chip. ScienceDaily . Retrieved June 2, 2025 from www.sciencedaily.com / releases / 2011 / 04 / 110422115850.htm ...

A new type of super-resolution optical microscopy takes a high-resolution image (at right) of graphite "nanoplatelets" about 100 nanometers wide. The imaging system, called saturated transient ...

Tenfold improvement of lateral resolution up to 20nm: N-STORM utilizes high accuracy localization information for thousands of individual fluorophores present in a field of view to create breathtaking ...

A key limitation of microscopes is that they can only image objects or details that are half the wavelength of the light used – so for optical microscopes, details can be seen down to about 200 ...