A new drug for pulmonary fibrosis has reduced disease progression by more than 50% over a 52-week treatment in two clinical ...

Saffron may spice up the sex lives of those taking a selective serotonin reuptake inhibitor who experience libido issues.

The novel PDE10A inhibitor CPL’36 offers a new mechanism of action and is both safe and effective for acute exacerbations of schizophrenia, new research suggests.

Analyses support Ohtuvayre® (ensifentrine) as a first-in-class selective dualinhibitor of PDE3 and PDE4 for a broad COPD population LONDON and RALEIGH, N.C., May 06, 2025 (GLOBE NEWSWIRE) -- Verona ...

Nuance Pharma’s Ohtuvayre has met the primary endpoint in a Phase III chronic obstructive pulmonary disease (COPD) study in ...

Q1 2025 net product revenue for ZORYVE® (roflumilast) was $63.8 million, a 196% increase compared to Q1 of 2024, and a 2% decrease compared to Q4 of 2024, due to typical first-quarter deductible reset ...

PDE1 (phosphodiesterase type 1) hydrolyzes cyclic adenosine and guanosine monophosphate. ITI-214 is a highly selective PDE1 inhibitor that induces arterial vasodilation and positive inotropy in larger ...

Despite these new medicines, there are still patients who might benefit from a more selective approach to treatment given ... The possibility that inhibiting certain phosphodiesterase (PDE) isoenzymes ...