The ;study showed that patients having tumors with inactivating mutations in PPP2R1A - the major scaffold subunit of protein ...

Glucose-6-phosphatase (G6Pase) catalyzes the hydrolysis of glucose-6-phosphate to glucose, the terminal step in both the gluconeogenic and glycogenolytic pathways.

Cold exposure is shown to aggravate osteoarthritis (OA) by suppressing chondrocyte APOE, triggering lipid accumulation, ...

Pipeline Therapies, Drugs Sales, and Regional Outlook The report provides a detailed analysis of the current apraxia marketed ...

The authors study how apolipoprotein L1 variants impact inflammation and lipid accumulation in macrophages. The findings will be useful for researchers investigating macrophage metabolism and ...

For example, the interaction of MKP3 with its specific substrate ERK2 enhances the phosphatase activity of MKP3 by almost 30-fold 28.

Steatotic liver disease often progresses asymptomatically, with the risk of advancing to cirrhosis and liver cancer. Early ...

These findings highlight the dual roles of antioxidants in cancer. Their impact depends on cancer type, stage, and genetic ...

Science Space Solar System Deep space asteroid sample contains unexpected ingredient Planetary scientists likened it to 'finding a tropical seed in Arctic ice.’ Andrew Paul Jun 23, 2025 11:30 AM EDT ...

Antibody–siRNA conjugates (ARCs) are a type of promising drug modalities for cancer therapy. However, initial reports of ARCs present the gene knockdown effect only in limited tissues (e.g., muscles) ...

Selecting a random sample from a set is simple. But what about selecting a fair random sample from a set of unknown or indeterminate size? That’s where reservoir sampling comes in, and [Sam R… ...

Radek Vitek is due back at Manchester United after his loan spell abroad ended, with the keeper hailed as a shining example to the younger Academy goalkeepers.