Low alkaline phosphatase levels may indicate several health concerns, including thyroid disease, malnutrition, pernicious anemia, and other conditions.

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Background and aims The intestinal microbiota plays a critical role in maintaining human health; however, the mechanisms governing the normal homeostatic number and composition of these microbes are ...

The alkaline phosphatase test is a common blood test that helps diagnose liver and bone disorders. Learn about its uses, procedure, and normal range.

Objectives Elevated baseline serum alkaline phosphatase (ALP) may correlate with higher medium-term to long-term mortality in the general population and in patients with chronic kidney disease.

THE acid phosphatase content of malignant prostatic tissue is regarded as an example of the retention by the neoplastic growth of a biochemical characteristic of the fully differentiated tissue of ...

An alkaline phosphatase isoenzyme (Regan isoenzyme) has been identified in the serum of 27 patients with various malignant tumors. This isoenzyme is biochemically and immunologically indistinguisha ...

Perturbation of protein phosphorylation represents an attractive approach to cancer treatment. Besides kinase inhibitors, protein phosphatase inhibitors have been shown to have anti-cancer activity. A ...

Alkaline phosphatase (ALP) is an enzyme that circulates in the blood. Here, learn what an ALP test involves, how to prepare, and what the results could mean.

As a specific example, we consider the cancer drug target PPM1D/Wip1 phosphatase, a protein that lacks crystal structures. High-throughput screens have led to the discovery of several allosteric ...

There are several liver enzymes that veterinarians will check on a routine basis. The two most common liver enzymes checked are called ALT (alanine aminotransferase) and ALP (alkaline phosphatase).