Phospholipase A2 (PLA2) enzymes are central regulators in cellular lipid metabolism, initiating the release of arachidonic acid from membrane phospholipids.

The quest for topical drugs that can provide a safe alternative to steroids leads to phospholipases, a family of enzymes that has been studied extensively. When will they replace topical steroids?

Indianapolis, IN - The latest effort to deploy phospholipase A2 (PLA2) inhibitors as anti-inflammatory agents in rheumatoid arthritis (RA) crashed and burned this month when Lilly Research ...

A groundbreaking study published in Genes & Diseases has revealed that exogenous pyruvate significantly alleviates the symptoms of ulcerative colitis ...