Mitotic kinase CDK1 phosphorylates LDHA at T18, reducing its incorporation into LDH tetramers and promoting formation of LDHB-enriched tetramers during mitosis. This accelerates lactate-to-NADH ...
A research group led by The University of Osaka has developed a novel method for analyzing cancer metabolism, revealing new ...
For the first time, scientists have described a way for cells to add phosphate groups to proteins that doesn't involve an ATP donor. A group at Johns Hopkins University in Baltimore synthesized ...
For the first time, scientists have described in this week's Science a way for cells to add phosphate groups to proteins that doesn't involve using adenosine triphosphate (ATP) as a donor. "Nobody had ...
"This is the first time we've seen one phosphorylation enzyme capable of handling such ... the enzyme grabs a pyrophosphate from ATP, briefly holds it on a histidine site, lets one phosphate go, and ...