Whereas all lipids are symmetrically distributed between the two leaflets of the ER membrane bilayer, the Golgi, plasma and endosomal membranes display an asymmetric lipid distribution with SM and ...

The plasma membrane is a lipid bilayer, the composition of which regulates frontier crossings by molecules between a cell's surroundings and its interior, ...

The plasma membrane is primarily composed of lipids and proteins, which are organized to be functionally dynamic supporting the changing needs of the cell, while also structured to maintain ...

Lipid bilayers in mammalian membranes can have a more asymmetric composition than previously thought, new research shows. This lipid abundance asymmetry is enabled by the unique properties of ...

'For the first time, we have succeeded in purifying and observing eisosomes containing plasma membrane lipids in their native state. This is a real step forward in our understanding of how they ...

Scientists have used cryo-electron microscopy to observe how lipids and proteins at the plasma membrane interact and react to mechanical stress. This work shows that, ...

This work shows that, depending on conditions, small membrane regions can stabilize various lipids to trigger specific cellular responses. These discoveries, published in the journal Nature ...

How muscle cells seal their membranes Date: March 14, 2012 Source: Karlsruhe Institute of Technology Summary: Every cell is enclosed by a thin double layer of lipids that separates the distinct ...

VP40 associates with plasma-membrane lipids such as phosphatidylserine (PS), and this association is critical to budding from the host cell. However, it is poorly understood how different VP40 ...

Lysosomes are surrounded by a lipid bilayer that separates the acidic environment and the digestive enzymes of the organelle from the cytoplasm. Damage to this layer—lysosomal membrane ...