A team has made a major breakthrough in the field of three-dimensional (3D) imaging of large-scale biological tissues. They ...

This useful study presents a biologically realistic, large-scale cortical model of the rat's non-barrel somatosensory cortex, investigating synaptic plasticity of excitatory connections under varying ...

Abstract Long-term potentiation (LTP) of synaptic strength can be induced by synchronous pre- and post-synaptic activation, and a rise in postsynaptic calcium is essential for induction of LTP.